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Users with hepatic impairment Neither semaglutide nor tirzepatide requires dose adjustment for mild to moderate hepatic impairment
A reasonable transition approach is to move from strict keto (under 25 grams net carbs) to a low-carbohydrate diet (50 to 100 grams net carbs) that is less restrictive but still meaningfully below the carbohydrate intake that drove the original weight gain
Changes in Manufacturing Models Small-molecule drugs are typically produced through chemical synthesis, which is more suitable for large-scale industrial manufacturing
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It is a new oral medication FDA approved to treat overweight and obesity
Expected Costs and Considerations Pricing for these medications once approved will likely reflect the premium pharmaceutical market for obesity treatments
